DMSO (dimethyl sulfoxide) has been studied and used experimentally for circulatory, cardiovascular, and neurological issues since the 1960s, though it is not FDA-approved for these purposes. Many natural and alternative practitioners consider it a powerful antioxidant, vasodilator, and anti-inflammatory that can help dissolve blood clots, increase oxygen delivery, and reduce ischemic damage. Below is a summary of common application methods historically or anecdotally used for the conditions you mentioned, based on the research and practices of pioneers such as Dr. Stanley Jacob, Dr. Morton Walker, and later popularized by Herb Roi Richards.
⚠️ Important Note
These methods are discussed for educational purposes only and should not replace qualified medical care. DMSO is a potent solvent that carries substances through the skin and must always be used with pharmaceutical or food-grade purity and diluted appropriately.
🧠 Stroke (Cerebrovascular Accident)
Goal: Rapid reduction of inflammation, restoration of blood flow, and prevention of clot propagation.
Common methods:
- Intravenous (clinical use):
In early hospital trials (Dr. Stanley Jacob, Oregon Health Sciences University), 10% to 30% DMSO IV solutions were infused to dissolve clots and reduce swelling. This was performed only under medical supervision. - Topical:
A 50% to 70% DMSO solution applied to the scalp, neck, and upper spine may aid circulation to the brain. Often applied 2–3 times daily for several days. - Oral:
1 teaspoon (about 5 mL) of 70% DMSO diluted in juice or water, once or twice daily, has been used to support microcirculation post-stroke.
❤️ Heart Attack (Myocardial Infarction)
Goal: Prevent further clotting, improve tissue oxygenation, and limit cardiac tissue damage.
Common methods:
- Topical over the chest:
A 50% solution applied directly over the heart area (upper left chest) to penetrate quickly. May be repeated every 4–6 hours initially. - Oral:
1–2 teaspoons of 70% DMSO diluted in 4–8 ounces of water or juice daily for 3–5 days, then reduced to a maintenance dose. - Injections (research use):
Dr. Jacob’s lab used 10% DMSO in sterile saline IV for acute events to restore oxygenation and prevent arrhythmias.
💔 Heart Failure (Congestive)
Goal: Reduce inflammation in cardiac tissue, improve oxygen utilization, and help remove metabolic waste.
Common methods:
- Topical:
50% DMSO solution over the chest and upper back once or twice daily.
(Some practitioners alternate with magnesium oil to support cardiac muscle relaxation.) - Oral:
½ to 1 teaspoon of 70% DMSO diluted in juice or distilled water daily.
This helps relieve tissue congestion and oxidative stress. - Foot Soak:
1 part 70% DMSO to 3 parts warm water for 20–30 minutes to enhance peripheral circulation.
⚡ Arrhythmias (Irregular Heartbeat)
Goal: Normalize electrical conductivity, improve electrolyte balance, and reduce inflammation in the cardiac conduction system.
Common methods:
- Topical:
50% DMSO rubbed on the chest and left arm (following the heart meridian) twice daily.
Sometimes combined with magnesium chloride or potassium-rich herbs. - Oral:
Small doses (¼–½ teaspoon of 70% DMSO in water daily) to improve systemic circulation. - Complementary:
Many report better rhythm stability when combined with Oceanic Magnesium (magnesium chloride) or coenzyme Q10.
💧 General Supporting Practices
| Application | Typical Dilution | Frequency | Notes |
| Topical | 50–70% | 1–3×/day | Apply to clean skin only. Expect warmth or mild itching. |
| Oral | 30–70% (½–1 tsp in juice/water) | 1–2×/day | Start low and increase gradually. |
| Foot/Hand Soaks | 25–50% | 20–30 min | Enhances peripheral circulation. |
| IV (Medical use) | 10–30% sterile solution | Doctor-supervised only | Used experimentally in emergencies. |

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